Isabelle DeBear Photo



Founding Director, Contracts Specialists

Industry Experience

Associate Director of Contracts

Millennium Pharmaceuticals, Inc. (now Takeda Pharmaceutical Company Limited)

Contracts Manager

Genetics Institute (acquired by Wyeth Research, now Pfizer)

Contracts Administrator

Parexel International

Contracts Associate

Cytomed, Inc.

Isabelle brings over 30 years of specialized contracts management and negotiation experience to Faber clients in the healthcare, biopharmaceutical, and high technology industries. She is the founder of the firm’s contracts specialists group, where she and our talented collection of professionals work with clients to develop efficient contracting processes and streamlined contract templates in the discovery, pre-clinical, and clinical phases of development.

In the clinical trial setting, Isabelle helps clients effectively resolve challenging issues, such as CRO changes during ongoing, multi-national clinical studies, transfers of studies among sponsors, and engagement of multiple sites in investigator- initiated studies. Her vast experience spans a wide-range of companies within the industry, including startups, clinical stage companies, contract research organizations, consulting groups, and big pharma. This valuable knowledge has provided her with a uniquely well- rounded perspective and understanding of day-to-day transactions common in the biopharmaceutical industry. As a result, Isabelle is frequently invited to speak at industry conferences on topics ranging from clinical trial subject injury issues to international considerations when contracting for clinical trials abroad.

experience +

experience –

Millennium Pharmaceuticals (now Takeda Pharmaceutical Company, Limited)

Associate Director of Contracts Administration

  • Member of the senior leadership team in the legal department
  • Worked with senior-level business and legal managers to create client-specific agreements to govern transactions common to the biopharmaceutical industry

Genetics Institute (now Pfizer)

Contracts Manager

  • Developed contract template and contracting process for novel data sharing program
  • Negotiated standard material transfer agreement to streamline provision of materials to large network of academic sites

Parexel International

Contracts Manager

  • Negotiated service agreements with major pharmaceutical companies wanting to engage Parexel as a CRO


  • Developed and implemented a contract tracking and management system

Recent Client Work +

Recent Client WOrk –

  • Phase 3 clinical trial sponsored by Deciphera Pharmaceuticals, LLC involving approximately 120 subjects across 35 sites worldwide
  • Phase 2 clinical trial sponsored by InflaRx GmbH. involving approximately 175 subjects across the US and Europe

Community +

Community –

Joe is or has been involved in a wide range of philanthropic and community organizations, including:

  • The Center for Discovery. Pro bono counsel for R&D initiatives at a leading provider of medical and clinical care and education services for people with complex developmental disabilities.
  • Dana-Farber Cancer Institute and Partners in Health. Pro bono counsel for an international health services joint venture.
  • Center for Maine Contemporary Art, Board of DirectorsTrustees.
  • Partners Healthcare Center for Personalized Genetic Medicine, Genetics Advisory Council, past member.
  • Columbia University’s College of Physicians and Surgeons, Medical Science and Technology Council, past member.
  • CAVU Foundation, Board of Directors, past member. CAVU  supported community programs that enhance the health care of underserved children in Massachusetts.
  • Venturing Out, Board of Directors, past member. Venturing Out was an innovative not-for-profit organization that taught entrepreneurship to incarcerated and court-involved adults and high-risk youth.
  • The Possible Project, Co-Founder of a not-for-profit that helps young people imagine, create and run their own business.
  • Slow Money, Maine and New York chapters. Joe worked with leadership to create pathways for individuals and families to provide financial assistance to farmers and agriculture businesses promoting sustainable local food systems. He also developed novel “patient loan” structures that have been used to raise critical financing for businesses that are re-building agricultural and fisheries food infrastructures.

Joe has spoken on business law and ethics at the Massachusetts Institute of Technology (Program of Health Sciences and Technology), Ross School of Business at the University of Michigan (Net Impact Conference), and Boston College Law School.

Joe was a member of the National Finance Council and actively involved in the voter protection team for the Stacey Abrams for Governor campaign.

  • Adelphi University, magna cum laude
  • Adelphi University, Paralegal Certificate with a specialty in Corporate Law
  • French